Ananya presented her Graduate Colloquium on Reductive Radical Polar Crossover. A short description on her presentation is given below
Reductive Radical-Polar Crossover (RRPCO) represents a rapidly evolving subset of photo redox catalysis, uniquely characterized by its capacity to merge radical and ionic reactivity within a single transformation. This approach enables the controlled conversion of radical intermediates into polar (typically anionic) species under reductive conditions, combining the advantages of radical pathways such as mild reaction conditions, broad functional group tolerance, and site-selectivity with the synthetic precision of polar mechanisms. This presentation will highlight recent advances in RRPCO methodologies aimed at constructing biologically relevant molecules under mild, sustainable conditions. Particular emphasis will be placed on the rational selection and tuning of photocatalysts based on their photophysical and redox properties to develop new, efficient reaction protocols. Finally, the current landscape and future prospects of RRPCO in synthetic organic chemistry was discussed.